1. Inicio
  2. Ciencia
  3. Publicaciones (2015-2020)
  1. Inicio
  2. Ciencia
  3. Publicaciones (2015-2020)

Publicaciones (2015-2020)

Más de 30 publicaciones científicas en los últimos 5 años


Topical treatment with sphingolipids and glycosaminoglycans for canine atopic dermatitis.

Marsella R. Segarra S, Ahrens K, Alonso C, Ferrer L. BMC Vet Res 16, 92 (2020).


Urine Metabolomic Analysis for Monitoring Internal Load in Professional Football Players.

Quintas G, Reche X, Sanjuan-Herráez JD, Martínez H, Herrero M, Valle X, Masa M, Rodas G. Metabolomics 16 (4) 45 DOI: 10.1007/s11306-020-01668-0


Bio-inspired hydrogel composed of hyaluronic acid and alginate as a potential bioink for 3D bioprinting of articular cartilage engineering constructs

Antich C, de Vicente J, Jiménez G, Chocarro C, Carrillo E, Montánez E, Gálvez-Martín P, Marchal

JA Acta Biomaterialia DOI


Role of mesenchymal stem cells as therapeutic agents: potential mechanisms of action and implications in their clinical use.

Jimenez-Puerta GJ; Marchal JA; Lopez-Ruiz E; Gálvez-Martín P.

J. Clin. Med. 

F.I.: 5.688; D1


A worldwide overview of regulatory frameworks for tissue-based products.

Oberweis C, Marchal JA, López-Ruiz E, Galvez-Martin P.

Tissue Eng Part B Rev. 2020 Jan 7. doi: 10.1089/ten.

TEB.2019.0315. (F.I.: 6.512; D1).


An overview of international regulatory frameworks for mesenchymal stromal cell-based medicinal products: From laboratory to patient.

López-Beas J, Guadix JA, Clares B, Soriano JL, Zugaza JL, Gálvez-Martín P.

Med Res Rev. 2020;0–0.

F.I.: 9.791; D1


Principal Criteria for Evaluating the Quality, Safety and Efficacy of hMSC-Based Products in Clinical Practice: Current Approaches and Challenges.

Guadix JA, López-Beas J, Clares B, Soriano JL, Zugaza JL, Gálvez-Martín P. Pharmaceutics 2019, 11(11), 552;


Cartilage biomechanics: A key factor for osteoarthritis regenerative medicine.

Martínez-Moreno D, Jiménez G, Gálvez-Martín P, Rus G, Marchal JA.

Biochim Biophys Acta Mol Basis Dis. 2019 Jun 1;1865(6):1067-1075. doi: 10.1016/j.bbadis.2019.03.011. Epub 2019 Mar 22. Review.

PMID: 30910703


Advances of hyaluronic acid in stem cell therapy and tissue engineering, including current clinical trials.

López-Ruiz E, Jiménez G, Álvarez de Cienfuegos L, Antic C, Sabata R, Marchal JA, Gálvez-Martín P.

Eur Cell Mater. 2019 Mar 19;37:186-213. doi: 10.22203/eCM.v037a12. Review.

PMID: 30889270


Differences in serum biomarkers between combined glucosamine and chondroitin versus celecoxib in a randomized, double-blind trial in osteoarthritis patients.

Navarro SL, Herrero M, Martinez H, Zhang Y, Ladd J, Lo E, Shelley D, Randolph TW, Lampe JW, Lampe PD.

Antiinflamm Antiallergy Agents Med Chem. 2019 Jan 14. doi: 10.2174/1871523018666190115094512. [Epub ahead of print]

PMID: 30648524


Volume-by-volume bioprinting of chondrocytes-alginate bioinks in high temperature thermoplastic scaffolds for cartilage regeneration.

Baena JM, Jiménez G, López-Ruiz E, Antich C, Griñán-Lisón C, Perán M, Gálvez-Martín P, Marchal JA.

Exp Biol Med (Maywood). 2019 Jan;244(1):13-21. doi: 10.1177/1535370218821128. Epub 2019 Jan 10.

PMID: 30630373


Therapeutic strategies for skin regeneration based on biomedical substitutes.

Chocarro-Wrona C, López-Ruiz E, Perán M, Gálvez-Martín P, Marchal JA.

J Eur Acad Dermatol Venereol. 2019 Mar;33(3):484-496. doi: 10.1111/jdv.15391. Epub 2019 Feb 22. Review.

PMID: 30520159


Chondroitin Sulphate Attenuates Atherosclerosis in ApoE Knockout Mice Involving Cellular Regulation of the Inflammatory Response.

Melgar-Lesmes P, Sánchez-Herrero A, Lozano-Juan F, de la Torre Hernández JM, Montell E, Jiménez W, Edelman ER, Balcells M.

Thromb Haemost. 2018 Jul;118(7):1329-1339. doi: 10.1055/s-0038-1657753. Epub 2018 Jun 6.

PMID: 29874688


Effectiveness of a low-fat yoghurt supplemented with rooster comb extract on muscle strength in adults with mild knee pain and mechanisms of action on muscle regeneration.

Moriña D, Fernández-Castillejo S, Valls RM, Pedret A, Taltavull N, Romeu M, Giralt M, Montero M, Bernal G, Faba J, Pérez-Merino L, Gonzalez R, Casajuana MC, Rodríguez Á, Arola L, Puiggrós F, Möller I, Chetrit C, Martinez-Puig D, Solà R.

Food Funct. 2018 Jun 20;9(6):3244-3253. doi: 10.1039/c8fo00286j.



β2‑adrenergic receptor functionality and genotype in two different models of chronic inflammatory disease: Liver cirrhosis and osteoarthritis.

Roca R, Esteban P, Zapater P, Inda MD, Conte AL, Gómez-Escolar L, Martínez H, Horga JF, Palazon JM, Peiró AM.

Mol Med Rep. 2018 Jun;17(6):7987-7995. doi: 10.3892/mmr.2018.8820. Epub 2018 Mar 29.

PMID: 29620176


Changes in serum anti-Leishmania antibody concentrations measured by time-resolved immunofluorometric assays in dogs with leishmaniosis after treatment.

Cantos-Barreda A, Escribano D, Martínez-Subiela S, Pardo-Marín L, Segarra S, Cerón JJ.

Vet Immunol Immunopathol. 2018 Apr;198:65-69. doi: 10.1016/j.vetimm.2018.03.003. Epub 2018 Mar 8.

PMID: 29571520


Prevention of disease progression in Leishmania infantum-infected dogs with dietary nucleotides and active hexose correlated compound.

Segarra S, Miró G, Montoya A, Pardo-Marín L, Teichenné J, Ferrer L, Cerón JJ.

Parasit Vectors. 2018 Feb 21;11(1):103. doi: 10.1186/s13071-018-2705-z.

PMID: 29467015


Chondroitin Sulfate Inhibits Monocyte Chemoattractant Protein-1 Release From 3T3-L1 Adipocytes: A New Treatment Opportunity for Obesity-Related Inflammation?

Stabler TV, Montell E, Vergés J, Huebner JL, Kraus VB.

Biomark Insights. 2017 Aug 24;12:1177271917726964. doi: 10.1177/1177271917726964. eCollection 2017.

PMID: 28890654


Heparin: new life for an old drug.

Aláez-Versón CR, Lantero E, Fernàndez-Busquets X.

Nanomedicine (Lond). 2017 Jul;12(14):1727-1744. doi: 10.2217/nnm-2017-0127. Epub 2017 Jun 21. Review.

PMID: 28635544


Randomized, allopurinol-controlled trial of the effects of dietary nucleotides and active hexose correlated compound in the treatment of canine leishmaniosis.

Segarra S, Miró G, Montoya A, Pardo-Marín L, Boqué N, Ferrer L, Cerón J.

Vet Parasitol. 2017 May 30;239:50-56. doi: 10.1016/j.vetpar.2017.04.014. Epub 2017 Apr 23.

PMID: 28495197


Encapsulation in Cell Therapy: Methodologies, Materials, and Clinical Applications.

Galvez-Martín P, Martin JM, Ruiz AM, Clares B.

Curr Pharm Biotechnol. 2017;18(5):365-377. doi: 10.2174/1389201018666170502113252. Review.

PMID: 28464772

Effects of chondroitin sulfate on brain response to painful stimulation in knee osteoarthritis patients. A randomized, double-blind, placebo-controlled functional magnetic resonance imaging study.

Monfort J, Pujol J, Contreras-Rodríguez O, Llorente-Onaindia J, López-Solà M, Blanco-Hinojo L, Vergés J, Herrero M, Sánchez L, Ortiz H, Montañés F, Deus J, Benito P.

Med Clin (Barc). 2017 Jun 21;148(12):539-547. doi: 10.1016/j.medcli.2016.12.036. Epub 2017 Feb 22. English, Spanish.

PMID: 2823761


Characteristics, applications and prospects of mesenchymal stem cells in cell therapy.

Guadix JA, Zugaza JL, Gálvez-Martín P.

Med Clin (Barc). 2017 May 10;148(9):408-414. doi: 10.1016/j.medcli.2016.11.033. Epub 2017 Jan 23. Review. English, Spanish.

PMID: 28126234


Evaluation of various biomarkers for kidney monitoring during canine leishmaniosis treatment.

Pardo-Marín L, Martínez-Subiela S, Pastor J, Tvarijonaviciute A, Garcia-Martinez JD, Segarra S, Cerón JJ.

BMC Vet Res. 2017 Jan 23;13(1):31. doi: 10.1186/s12917-017-0956-0.

PMID: 28114941


A 3-Arm Randomized Trial for Achilles Tendinopathy: Eccentric Training, Eccentric Training Plus a Dietary Supplement Containing Mucopolysaccharides, or Passive Stretching Plus a Dietary Supplement Containing Mucopolysaccharides.

Balius R, Álvarez G, Baró F, Jiménez F, Pedret C, Costa E, Martínez-Puig D.

Curr Ther Res Clin Exp. 2016 Nov 18;78:1-7. doi: 10.1016/j.curtheres.2016.11.001. eCollection 2016.

PMID: 28053674


Mesenchymal Stem Cells as Therapeutics Agents: Quality and Environmental Regulatory Aspects.

Galvez-Martin P, Sabata R, Verges J, Zugaza JL, Ruiz A, Clares B.

Stem Cells Int. 2016;2016:9783408. doi: 10.1155/2016/9783408. Epub 2016 Nov 24. Review.

PMID: 27999600


Changes in serum biomarkers of oxidative stress after treatment for canine leishmaniosis in sick dogs.

Rubio CP, Martinez-Subiela S, Tvarijonaviciute A, Hernández-Ruiz J, Pardo-Marin L, Segarra S, Ceron JJ.

Comp Immunol Microbiol Infect Dis. 2016 Dec;49:51-57. doi: 10.1016/j.cimid.2016.09.003. Epub 2016 Sep 15.

PMID: 27865264


Effect of chondroitin sulfate on soluble biomarkers of osteoarthritis: a method to analyze and interpret the results from an open-label trial in unilateral knee osteoarthritis patients.

Möller I, Gharbi M, Martinez Serrano H, Herrero Barbero M, Verges Milano J, Henrotin Y.

BMC Musculoskelet Disord. 2016 Oct 6;17(1):416.

PMID: 27716158


Chondroitin sulphate inhibits NF-κB activity induced by interaction of pathogenic and damage associated molecules.

Stabler TV, Huang Z, Montell E, Vergés J, Kraus VB.

Osteoarthritis Cartilage. 2017 Jan;25(1):166-174. doi: 10.1016/j.joca.2016.08.012. Epub 2016 Sep 7.

PMID: 27614315


Effects of sphingolipid extracts on the morphological structure and lipid profile in an in vitro model of canine skin.

Cerrato S, Ramió-Lluch L, Brazís P, Fondevila D, Segarra S, Puigdemont A.

Vet J. 2016 Jun;212:58-64. doi: 10.1016/j.tvjl.2016.03.020. Epub 2016 Mar 30.

PMID: 27256026


The use of porcine digestible peptides and their continuity effect in nursery pigs.

Figueroa J, Solà-Oriol D, Guzmán-Pino SA, Chetrit C, Borda E, Pérez JF.

J Anim Sci. 2016 Apr;94(4):1531-40. doi: 10.2527/jas.2015-0019.

PMID: 27136012


Chondroprotective effects of the combination chondroitin sulfate-glucosamine in a model of osteoarthritis induced by anterior cruciate ligament transection in ovariectomised rats.

Terencio MC, Ferrándiz ML, Carceller MC, Ruhí R, Dalmau P, Vergés J, Montell E, Torrent A, Alcaraz MJ.

Biomed Pharmacother. 2016 Apr;79:120-8. doi: 10.1016/j.biopha.2016.02.005. Epub 2016 Feb 18.

PMID: 27044820


Oral chondroitin sulfate and prebiotics for the treatment of canine Inflammatory Bowel Disease: a randomized, controlled clinical trial.

Segarra S, Martínez-Subiela S, Cerdà-Cuéllar M, Martínez-Puig D, Muñoz-Prieto A, Rodríguez-Franco F, Rodríguez-Bertos A, Allenspach K, Velasco A, Cerón J.

BMC Vet Res. 2016 Mar 10;12:49. doi: 10.1186/s12917-016-0676-x.

PMID: 26965834


Treatment with chondroitin sulfate to modulate inflammation and atherogenesis in obesity.

Melgar-Lesmes P, Garcia-Polite F, Del-Rey-Puech P, Rosas E, Dreyfuss JL, Montell E, Vergés J, Edelman ER, Balcells M.

Atherosclerosis. 2016 Feb;245:82-7. doi: 10.1016/j.atherosclerosis.2015.12.016. Epub 2015 Dec 13.

PMID: 26714044


Rac1/p21-activated kinase pathway controls retinoblastoma protein phosphorylation and E2F transcription factor activation in B lymphocytes.

Zaldua N, Llavero F, Artaso A, Gálvez P, Lacerda HM, Parada LA, Zugaza JL.

FEBS J. 2016 Feb;283(4):647-61. doi: 10.1111/febs.13617. Epub 2016 Jan 4.

PMID: 26663827


A DIGE proteomic analysis of wheat flag leaf treated with TERRA-SORB® foliar, a free amino acid high content biostimulant

Martinez-Esteso, M.J., Vilella-Anton, M.T., Selles-Marchart, S., Martinez-Marquez, A., Botta-Catala, A., Pinol-Dastis, R., Bru-Martinez, R.

Journal of Integrated OMICS, 2016 6 (1), pp. 9-17. doi: 10.5584/jiomics.v6i1.188


Understanding the effect of amino acids based biostimulant by an enantiomeric analysis of their active principles and a proteomic profiling approach​

Sierras, N., Botta, A., Staasing, L., Martinez, M.J., Bru, R

Acta Horticulturae, 2016 1148, pp. 93-100. doi: 10.17660/ActaHortic.2016.1148.11


A low-fat yoghurt supplemented with a rooster comb extract on muscle joint function in adults with mild knee pain: a randomized, double blind, parallel, placebo-controlled, clinical trial of efficacy.

Solà R, Valls RM, Martorell I, Giralt M, Pedret A, Taltavull N, Romeu M, Rodríguez À, Moriña D, Lopez de Frutos V, Montero M, Casajuana MC, Pérez L, Faba J, Bernal G, Astilleros A, González R, Puiggrós F, Arola L, Chetrit C, Martinez-Puig D.

Food Funct. 2015 Nov;6(11):3531-9. doi: 10.1039/c5fo00321k. Epub 2015 Aug 24.

PMID: 26302034


Synergistic Effects of a Mixture of Glycosaminoglycans to Inhibit Adipogenesis and Enhance Chondrocyte Features in Multipotent Cells.

Petrov PD, Granados N, Chetrit C, Martínez-Puig D, Palou A, Bonet ML.

Cell Physiol Biochem. 2015;37(5):1792-806. doi: 10.1159/000438542. Epub 2015 Nov 13.

PMID: 26584280



Chondroitin Sulfate Induces Depression of Synaptic Transmission and Modulation of Neuronal Plasticity in Rat Hippocampal Slices.

Albiñana E, Gutierrez-Luengo J, Hernández-Juarez N, Baraibar AM, Montell E, Vergés J, García AG, Hernández-Guijo JM.

Neural Plast. 2015;2015:463854. doi: 10.1155/2015/463854. Epub 2015 May 13.

PMID: 26075099


Effects of BIS076 in a model of osteoarthritis induced by anterior cruciate ligament transection in ovariectomised rats.

Ferrándiz ML, Terencio MC, Carceller MC, Ruhí R, Dalmau P, Vergés J, Montell E, Torrent A, Alcaraz MJ.

BMC Musculoskelet Disord. 2015 Apr 17;16:92. doi: 10.1186/s12891-015-0547-9.

PMID: 25903377


A genetic predictive model for canine hip dysplasia: integration of Genome Wide Association Study (GWAS) and candidate gene approaches.

Bartolomé N, Segarra S, Artieda M, Francino O, Sánchez E, Szczypiorska M, Casellas J, Tejedor D, Cerdeira J, Martínez A, Velasco A, Sánchez A.

PLoS One. 2015 Apr 13;10(4):e0122558. doi: 10.1371/journal.pone.0122558. eCollection 2015.

PMID: 25874693


Discrepancies in composition and biological effects of different formulations of chondroitin sulfate.

Martel-Pelletier J, Farran A, Montell E, Vergés J, Pelletier JP.

Molecules. 2015 Mar 6;20(3):4277-89. doi: 10.3390/molecules20034277. Review.

PMID: 25756648


Improved prediction of knee osteoarthritis progression by genetic polymorphisms: the Arthrotest Study.

Blanco FJ, Möller I, Romera M, Rozadilla A, Sánchez-Lázaro JA, Rodríguez A, Gálvez J, Forés J, Monfort J, Ojeda S, Moragues C, Caracuel MÁ, Clavaguera T, Valdés C, Soler JM, Orellana C, Belmonte MÁ, Martín F, Giménez S, Úcar E, Pous J, Bartolomé N, Artieda M, Szczypiorska M, Tejedor D, Martínez A, Montell E, Martínez H, Herrero M, Vergés J; Arthrotest Study Group.

Rheumatology (Oxford). 2015 Jul;54(7):1236-43. doi: 10.1093/rheumatology/keu478. Epub 2015 Jan 7.

PMID: 25573839


Para obtener más información acerca de nuestras publicaciones.